The use of aspirin in Covid-19 patients

[Honoria]

Aspirin Reduces Ventilation And Deaths In Hospitalized COVID-19 Patients


By Josh Bloom — June 15, 2021

Simple, inexpensive drugs to treat COVID are few and far between. But we may have a new, old pill to add to the arsenal. A new study tells us how well it works.



One of the earliest (of many) bizarre symptoms of COVID-19 was blood clotting in the lungs. These clots could easily be seen when an endotracheal tube was removed from a ventilated patient. The tube was coated with a whole lot of mucus with red streaks. Not so pleasant to look at.



Naturally, heparin, an anticoagulant, was tried. A modest positive effect on survival was seen in a large retrospective study reported in BMJ in February. But heparin is tricky to use. It is considered to be a high-risk drug because both over-and underuse can be fatal.



Aspirin, another blood thinner, is a safer and cheaper alternative in that it can be given orally or IV and does not carry the same risks as heparin or warfarin. But is it effective in treating COVID-19 patients? A new observational study concludes that it is.



Jonathan Chow, MD, University, and colleagues concluded that aspirin was useful in keeping people off ventilators and preventing COVID-19 deaths. Here is a summary of their findings.



412 patients were included in the study

314 did not receive aspirin, 98 did.

The 98 patients who received aspirin were a combination of those who were already taking aspirin before hospitalization and those given it following hospitalization.

After adjusting for 8 confounders, the use of aspirin was associated with a 44% decrease in ventilation, a 43% decrease in ICU admission, and a 47% decrease in deaths (in the hospital).

There was no difference in serious bleeding between the two groups.


“The results of the study do not really surprise us because we know that COVID causes excess clot formation and we know that aspirin is a very potent blood thinner...so when you have a disease that causes clots and a medication that thins your blood, that may lead to the protective effects that we found.”



Jonathan Chow, M.D.

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[Honoria]

OK, now that honest, reputable doctors have established aspirin's usefulness, here comes the same government that is demonizing proven treatments such as Ivermectin and Hydroxychloroquine

Feds: Stop taking daily aspirin!


So since there has been evidence of it helping with COVID, the feds say "No More!" even though it has been recommended to help prevent heart attacks for years.  Anyone else finding the timing suspicious?

US task force proposes adults 60 and older should not take daily aspirin to prevent heart disease or stroke



By Jacqueline Howard, CNN



Updated 12:57 PM ET, Tue October 12, 2021

Studies: Low-dose aspirin risks may outweigh benefits

Like this wasn't studied before? Now all of a sudden it's "dangerous?"


(CNN)The US Preventive Services Task Force is considering making several changes to its guidance on taking a daily aspirin to prevent heart disease and stroke.



On Tuesday, the task force posted a draft statement recommending that adults ages 40 to 59 who are at a higher risk for cardiovascular disease -- but do not have a history of the disease -- decide with their clinician whether to start taking aspirin, based on their individual circumstances.

This is the first time the task force has recommended that adults in their 40s talk to their doctors about whether to take aspirin for heart health.


Healthy people shouldn't take daily aspirin to prevent heart disease, review finds

Healthy people shouldn't take daily aspirin to prevent heart disease, review finds

The draft also says that adults 60 and older should not start taking aspirin to prevent heart disease and stroke because new evidence shows that potential harms cancel out the benefits, according to the task force.


"The latest evidence is clear: starting a daily aspirin regimen in people who are 60 or older to prevent a first heart attack or stroke is not recommended," Task Force member Dr. Chien-Wen Tseng said in a statement. "However, this Task Force recommendation is not for people already taking aspirin for a previous heart attack or stroke; they should continue to do so unless told otherwise by their clinician."


The draft recommendation was posted for public comments, which can be submitted from now to November 8.


Heart disease is the leading cause of death in the United States, causing about 1 in 4 deaths. While taking a daily low-dose aspirin has been shown to lower the risk of having a heart attack or stroke in some people, doing so also comes with the serious risk of potential bleeding in the stomach, intestines and brain, according to the task force. That risk of bleeding increases with age.

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